18 Seen clauses No. 1, 3, 4, 5, 6, 8, 9, 11, 13, 14, 16, 17, 18, 20, 21, 22 and 23), it can be clearly inferred that, in spite of the measures adopted by the State to improve detention conditions (supra Having Seen clauses No. 3(o), 3(p), 3(q), 3(r), 4, 8, 9, 11, 14, 16(a), 16(f), 16(g), 16(l), 17(g), 20(a), 20(b), 20(c) and 22), the extreme serious and urgent conditions and the possibility of irreparable damage to the rights to life and personal integrity of La Pica inmates still exist. Specially, it is worth pointing out that during year 2005, 43 inmates died due to acts of violence committed in La Pica Confinement Center, and 25 inmates were injured (supra Having Seen clause No. 3(b)), and by this date of year 2006, other three detainees died and one was injured (supra Having Seen clauses No. 13, 16(b), 17(b) and 18). That pursuant to the information furnished by the parties it can be inferred that the factors that generate the serious conditions and the risk for La Pica detainees are the overcrowding, the lack of separation of inmates by categories, the deficient sanitary, physical and safety conditions they are subject to, and the lack of personnel duly trained and qualified (supra Having Seen clauses No. 3, 5, 16, 17, 20, 21 and 22). Moreover, the situation is aggravated by the lack of control of the introduction and possession of arms within the confinement center (supra Having Seen clauses No. 3(d), 3(g), 5(i), 14(f), 16(g), 17(f), 17(h), 20(d) and 21(c)). 12. That the State has expressed that it agrees with the Commission that the situation described in the instant case is critical. Besides, according to the information furnished by the State, several measures have been or are being adopted with the purpose of safeguarding the life and physical integrity of the penitentiary population in Venezuela, mainly at La Pica Confinement Center, as well as of improving the imprisonment conditions of said population (supra Having Seen clauses No. 8, 9, 11, 14 and 22). Among said measures we can point out the creation of the Comisión Presidencial para Atender la Emergencia Carcelaria (Presidential Committee for Jail Emergency), the appropriation of funds for improving the infrastructure of the Confinement Center, as well as the training of the jail system officers, the several searches and seizures conducted in search of arms within the confinement center, the enhancement of food and health care services for inmates, the review and overruling of rules of the Organic Code of Criminal Procedure, and the investigation of the acts of violence occurred in the Confinement Center, among other measures. 13. That the positive participation of the State, the Commission and the representatives at the public hearing held in the instant case is a significant advance in the development of these proceedings and contributes to the effectiveness of the principles enshrined in the American Convention. 14. That the State must protect and respect the functions that may be exercised by non-governmental entities and by other groups or individuals that defend human rights and the essential liberties of persons deprived of liberty, since said actions are a positive contribution and a supplement to all efforts made by the State in its capacity of guarantor of the rights pertaining to the persons held under its custody. 15. That, under the circumstances of the instant case, the Commission alleges that several detainees have died and have been injured as result of the fights among inmates.