44 2. Conduct a thorough, impartial, and effective investigation into the facts to determine the responsibility and to punish all the perpetrators of the human rights violations to the detriment of the victims in the instant case, including the investigations necessary to determine the responsibility and punish the persons who participated in covering up the facts and in the denial of justice. 3. Make adequate reparation to the victims of the instant case, including both the material and non-material aspect. 4. Adopt the measures necessary for ensuring the effectiveness and permanence for the time necessary of the search commission, the search webpage, and the genetic information system being implemented in the framework of what was ordered by the Inter-American Court of Human Rights in the judgment of the case of the Serrano Cruz Sisters. In particular, ensure that these measures are established through the legal mechanisms that provide legal certainty in its functioning and sufficient budget. 5. Adopt non repetition measures to ensure that the integral protection system of children is implemented effectively, including the strenghtening and adequacy with the internacional standards of the Civil Registry system and the adoption system.