-33. The arguments of the Commission to justify its request for provisional measures, wherein it stated that: a. b. c. d. the facts against Ms. Guerrero-Gallucci foreshadow acts against her life and personal integrity, due to her denouncement activities (supra Having Seen clauses No. 2(b) and (c)); even though the State has adopted measures of protection in favor of the beneficiaries, according to the information furnished by the petitioners, the protection provided is not sufficiently adequate to effectively protect beneficiaries’ lives. Threats became true “in the form of extremely grave acts against physical integrity aimed at deprivation of life;” it ratified its deep concern for the alleged hostility and threats against the life and physical integrity of human rights defenders in Venezuela; and the special impact of aggressions against the right to life of human rights defenders lies in that their damaging effect reaches much beyond the direct victims. 4. The request of the Inter-American Commission so that the Court, based on Article 63(2) of the American Convention, may call upon the State to: a. adopt, forthwith, whatever measures are necessary to safeguard beneficiaries’ lives and personal integrity, in keeping with the requirements and means described herein; b. allow the beneficiaries and their representatives to participate in the planning and implementation of the measures of protection; c. conduct serious, complete and prompt investigations into the acts of aggression against the beneficiaries, identify those responsible and impose on them the corresponding punishment, as a prevention mechanism to avoid the recurrence of threats or the occurrence of irreparable damage to the beneficiaries; and d. report, as soon as possible, on any progress made in and the outcome of the investigations undertaken to identify and punish those responsible for the facts giving rise to the request. 5. The note of Secretariat of the Court (hereinafter "the Secretariat") of June 21, 2006, wherein, as instructed by the President, in consultation with the full Court, the State was granted a term ending on June 23, 2006 to submit its comments on the request for provisional measures submitted by the Commission (supra Having Seen clause No. 1). 6. The brief of June 28, 2006, wherein the State submitted the comments that had been requested through instructions of the President of the Court. In said brief, the State expressed, inter alia, that: a. on April 22, 2006, Control Court No. 1 ordered a measure of protection for a 90-day renewable term in favor of Ms. Guerrero- Gallucci and Mr. Martínez-Barrios. Officers from the Office of the Cuerpo de Investigaciones Científicas Penales y Criminalísticas de la Sub-