4 8. That, in the instant case, the irreparable nature of the extremely serious and urgent threat relates to the right to life and humane treatment. In addition, the Court notes that the testimony given by Mr. Dencen Andino Alvarado in the domestic proceedings is related to the subject matter of this case. 9. That, based on the facts as presented before the Court by the representatives during the proceedings regarding the instant case, the situation of Mr. Dencen Andino Alvarado is, prima facie, one of extreme gravity and urgency that require the adoption of measures of protection in order to prevent irreparable damage to him. The foregoing will allow Mr. Andino Alvarado to be safe during the investigation and the proceedings in the criminal case in which he is a witness. The necessary measures to be adopted must effectively prevent Mr. Andino Alvarado’s loss of life and injury to his physical integrity. Therefore, The Inter-American Court of Human Rights, in accordance with Article 63(2) of the American Convention on Human Rights and by virtue of the authority vested in it by Article 25 of the Rules of Procedure, Decides: 1. To require the Republic of Honduras to adopt, without delay, such measures as may be necessary to effectively ensure the protection of Mr. Dencen Andino Alvarado’s life and physical integrity. 2. To call upon the Government of the Republic of Honduras to adopt such measures as may be necessary to ensure that Mr. Dencen Andino Alvarado is not persecuted or threatened as a result of his participation as a witness in the investigation conducted by the authorities in the case regarding the murder of Blanca Jeannette Kawas Fernández, as set forth in Considering Clause No. 9 of this Order. 3. To require the State that the measures of protection ordered herein be designed and implemented with the participation of the beneficiaries of such measures or their representatives. 4. To call upon the State to provide information to the Inter-American Court of Human Rights, every two months, regarding the provisional measures adopted, and to request the beneficiaries of these measures or their representatives and the InterAmerican Commission on Human Rights to submit their comments on the State’s bimonthly reports, within four and six weeks respectively, following receipt thereof. 5. To request the Secretariat of the Court to notify this Order to the State, the Inter-American Commission on Human Rights, the beneficiary of these measures and his representatives.