situation is one of extreme gravity and requires the State’s immediate and effective response; c) regarding the standard of extreme urgency, the Commission noted that “the alleged failure to ensure adequate measures of protection and the alleged lack of progress in the investigation of the threats and violence against Margarita MartínezMartínez –allegedly committed or tolerated by State agents— are elements that support this requirement;” d) that the Court should take into consideration the lack of concrete effects of the precautionary measures as a factor to presume that a person’s situation is grave; e) that it considers it important to highlight the essential role played by human rights defenders in society and the crucial need to protect their “life, personal integrity, personal liberty, and freedom of expression.” It also stated that “the special impact of the attacks against human rights defenders lies in its harmful effect, which goes beyond the direct victims,” and f) that given the Court’s constant practice of using the prima facie assessment standard and the application of presumptions to the immediate requirements for protection, the Court has sufficient information to admit the request for provisional measures. 6. The communication of November 25, 2011, in which the Secretariat of the Court (hereinafter "the Secretariat") sent a copy of the request for provisional measures to the State. Also, following the instructions of the plenary of the Court, it requested that the State submit, no later than December 5, 2011, any observations it deemed relevant regarding the request, as well as any other information or documentation deemed appropriate, in order for the Court to consider the Commission’s request with all the necessary information. 7. The brief of December 6, 2011, in which the State referred “to the request for information concerning the situation of Mrs. Margarita [...] Martínez Martínez, her husband Adolfo Guzmán Ordaz, and their children [...], in order to assess the admissibility of a request for provisional measures in her favor.” In this regard, the State submitted its observations on the various facts noted by the Commission in its request for provisional measures. These are: Events that took place prior to the adoption of precautionary measures a) regarding the alleged events of November 8, 2009, the State indicated that on November 23, 2009, Mr. Adolfo Guzmán Ordaz and Mrs. Margarita Guadalupe Martínez Martínez filed a formal written complaint before “the Special Prosecutor for Protection and Assistance of Nongovernmental Organizations for the Defense of Human Rights (hereinafter “FEPAONGDDH” for its Spanish acronym), for the crimes of Torture, Raiding Premises, Abuse of Authority and any crimes that might be committed to their detriment, and against the person or persons responsible.” The State specified that “at this time, FEPAONGDHH offered to implement precautionary measures to ensure the physical integrity of Mr. Adolfo Guzmán Ordaz and his family, to prevent a situation that is difficult or impossible to remedy, which were not accepted by the offended party.” 5